Though the authors of the BSR blog don’t comment on the topic frequently, there’s an undercurrent of ethical debate to the vast majority of scientific issues. Sometimes the ethical debate is obvious, as in these recent pieces on Proposition 37. In other cases, it’s more subtle: all research needs to justify the money spent on it—money that could otherwise go to other efforts at improving the human condition. In the particular case of Alzheimer’s, the ethics of diagnosis have increasingly become critical. I want to pause for a moment from science, and think about a few of the shifting considerations of this case brings.

Alzheimer’s disease causes the slow degradation of the mental faculties, leading to dementia and death. This decline places an enormous burden on caregivers, often family members, and makes AD the third most economically expensive disease in the developed world. Because onset of the disease typically begins after age 65, it has been an increasing concern as the human lifespan lengthens. Though some are in trials, there are no known treatments that cure or even simply slow the progress of Alzheimer’s.